The amytriptaline was supposed to reduce the pain messages to the brain that she claims are hyper vigilant and misfiring. After about two weeks I had to get off the medication due to an increased sensation of depression and anxiety. That medication is definitely not for me, though when I quit it, it seemed to me that it might have been causing a reduction in pain symptoms. In other words, my pain seemed to increase when I went off the amytriptaline. It's hard to be sure because my pain fluctuates anyway.
As for the physical therapy, I can't recommend it enough. Pelvic tension was found to be a big player in my IC symptoms, and my retention issues are, at least for the time being, gone. IC sisters will be developing a yoga video of helpful exercises, but in the meantime, consider seeing a physical therapist that specializes in Interstitial Cystitis.
There are many blogs where people share their experiences with TENS Units curing their IC pain, so other IC sufferers have also discovered a muscular-IC pain link. In the eighties I took Hytrin, a smooth muscle relaxer which also eased my symptoms some. There is quite a bit of evidence supporting the theory of a muscular component to IC pain, and from my own experience, I feel you must know that if you suffer from retention you should give physical therapy a try.
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